Ameloblastoma is a rare, benign or cancerous tumor of odontogenic epithelium much more commonly appearing in the lower. Histopathology of ameloblastoma of the jaws; some critical observations based on a 40 years single institution experience. Doenja Hertog 1. Cases Series. Rui Henriques Martins Josias de Andrade Sobrinho AbrĂ£o Rapoport Marilene Paladino Rosa. Histopathologic features and management of .

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Most patients thus typically present with a complaint of swelling and facial asymmetry.

Pathology Outlines – Benign tumors / tumor-like conditions: ameloblastoma

Parts of the epithelial lining of a uni cystic ameloblastoma may lack the pathognomonic features an ameloblastoma. Oral and Maxillofacial surgery clinics of North America.

The radiodensity of an amelioblastoma is about 30 Hounsfield unitswhich is about the same as keratocystic odontogenic tumours. This variant histologically presents as a single cyst lined by ameloblastomatous epithelium and is divided into several subgroups based on pattern and extent of ameloblastomatous proliferation in relation amelonlastoma cyst wall. Bony septae may result in a honeycomb appearance.

Often, treatment requires excision of entire portions of the jaw. Figure 5C and D: J Oral Maxillofac Surg. In several hsitopathology the presence of ameloblastomalike cells in follicles of asymptomatic third molars has amelloblastoma reportedthe percentages varying from 1. Additionally, because abnormal cell growth easily infiltrates and destroys surrounding bony tissues, wide surgical excision is required to treat this disorder. There is conflicting evidence on the incidence rates in different races.

Sign up for our Email Newsletters. Multicystic ameloblastoma is also referred to as conventional or infiltrating ameloblastoma. There are no specific genetic alteration reported that indicate an increase risk in development of ameloblastoma. Angadi, PV Head, Neck: This has been corroborated in the new classification from Philipsen and Reichart.


The plexiform ameloblastoma shows epithelium proliferating in a ‘cord like fashion’, hence the name ‘plexiform’. Ameloblatoma cytologically usually presents with basaloid cells arranged in cells and clusters. Lifelong follow up is strongly recommended. They are rare in children 8. Archived histopatholigy the original on It shows equal sex predilection with no specific racial predominance.


Odontogenic ameloblastoma OA of the jaws is a rare neoplasia of the oral cavity 0. The histopathological typing of the biopsies and surgical specimens has been performed by one experienced oral pathologist. Comparing our results with the literature demonstrated to us that this tumor may be considered to be a worldwide problem due to the similarity in clinical findings among different ethnic groups. Int J Oral Maxillofac Surg. Histochemical evaluation of the collagen suggests that the dense stroma is not scar tissue but represents active denovo synthesis of extracellular matrix proteins.

Sometimes this change, may be so extensive that the peripheral columnar cells may also be replaced making the diagnosis difficult especially in a small biopsy.

Falkson gave a detailed description in Odontogenic epithelial islands composed of: Figure 1 – Photomicrograph of follicular ameloblastoma hematoxylin eosin x From Wikipedia, the free encyclopedia. J Oral Surg ; Nine patients were initially diagnosed with a benign ameloblastoma but have been excluded because of extra-osseous localization 1 patient or because of doubt about the correct diagnosis of ameloblastoma in the initial lesion 8 patients.

Unknown and somewhat controversial, but leading hypotheses include remnants of dental lamina, basal layer of oral mucosa and, less commonly, arising within pre-existing dentigerous cyst. Nevertheless, Feinberg and Steinberg 9 indicate different surgical margins for resections depending on the anatomical location and esthetic involvement.


Cytogenetics Note There are no specific genetic alteration reported that indicate an increase risk in development of ameloblastoma. Austr Dent J ; Am Assoc Dent Sch Trans. According to Williams, 8 the therapeutic model and treatment of these tumors depends on their size. Extra-osseous occurrence is rather exceptional.

For statistical analysis, the hypothesis test was used for relating the results from our group to those in the literature. However, unicystic ameloblastoma typically presents as a unilocular radiolucency containing an impacted tooth.

Ameloblastoma – Libre Pathology

Dalati T, Zhou H. The plexiform type has epithelium that proliferates in a “Fish Net Pattern”. CT scans showing buccal cortical plate expansion.

It is considered to be the most common odontogenic tumor. The anatomopathological classification of the ameloblastoma is not yet routine, but we are convinced that dealing with the differences in histologic patterns ameloblastma relevant in establishing surgical procedures, from the simplest biopsies and bone scraping to the most invasive acts. In the maxilla it can extend into the maxillary sinus and floor of the nose. It is, indeed, often difficult to remove a cystic lesion in tot without fragmentation.